Invention Grant
- Patent Title: Aza-heteroaryl compounds as PI3K-gamma inhibitors
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Application No.: US15414931Application Date: 2017-01-25
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Publication No.: US10022387B2Publication Date: 2018-07-17
- Inventor: Ge Zou , Andrew P. Combs , Andrew W. Buesking
- Applicant: Incyte Corporation
- Applicant Address: US DE Wilmington
- Assignee: Incyte Corporation
- Current Assignee: Incyte Corporation
- Current Assignee Address: US DE Wilmington
- Agency: Fish & Richardson P.C.
- Main IPC: A61K31/675
- IPC: A61K31/675 ; A61K31/423 ; A61K31/437 ; A61K31/4439 ; A61K31/4545 ; A61K31/4709 ; A61K31/495 ; A61K31/506 ; A61K31/5377
Abstract:
The present invention provides aza-heteroaryl derivatives of Formula I: and pharmaceutically acceptable salts thereof, wherein X, Y, Z, A, W, R4, R5, and R6 are defined herein, that inhibit the activity of phosphoinositide 3-kinases-gamma (PI3Kγ) and are useful in the treatment of diseases related to the activity of PI3Kγ including, for example, autoimmune diseases, cancer, cardiovascular diseases, and neurodegenerative diseases.
Public/Granted literature
- US20170232016A1 AZA-HETEROARYL COMPOUNDS AS PI3K-GAMMA INHIBITORS Public/Granted day:2017-08-17
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