A zero-point fixture is a means for securing a component in place during machining. The fixture features a base plate that is placed onto a machining surface and a mounting plate to which the component may be attached. The mounting plate and the component are secured to the base plate by operatively engaging a plurality of retention knobs on the mounting plate into a plurality of pressurized clamps on the base plate. A plurality of mounting holes and a plurality of mounting channels allow the component to be mounted in a number of positions and orientations that may be reproduced for subsequent components to be machined. A plurality of risers serves to offset the component from the mounting plate while a plurality of elongated fasteners is inserted into the component to prevent movement of the component during machining.