Invention Grant
- Patent Title: Method and device for manufacturing lactide
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Application No.: US15570244Application Date: 2016-04-28
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Publication No.: US10023553B2Publication Date: 2018-07-17
- Inventor: Johannes Jeichienus De Vries , Ana Isabel Cavaco Morao , Andre Banier De Haan
- Applicant: PURAC BIOCHEM BV
- Applicant Address: NL Gorinchem
- Assignee: PURAC BIOCHEM BV
- Current Assignee: PURAC BIOCHEM BV
- Current Assignee Address: NL Gorinchem
- Agency: Oliff PLC
- Priority: EP15166019 20150430
- International Application: PCT/EP2016/059539 WO 20160428
- International Announcement: WO2016/174161 WO 20161103
- Main IPC: C07D319/12
- IPC: C07D319/12 ; B01D3/34 ; B01D3/42 ; B01J19/00

Abstract:
A method and a device for manufacturing lactide, whereby crude lactide, being prepared by means of depolymerization of lactic acid oligomers, is purified by means of a distillation step. The prepared crude lactide is maintained for a period of at least 5 hours in a reaction vessel at a temperature between 97° C. and 200° C. prior to the distillation step. Keeping the lactide during a period of time in a reaction vessel leads to a decrease of the lactic acid content and an increase of the lactic acid oligomer concentration, so that the resulting crude lactide can be more efficiently purified during subsequent distillation. A pre-distilling step gives additional advantages.
Public/Granted literature
- US20180155313A1 METHOD AND DEVICE FOR MANUFACTURING LACTIDE Public/Granted day:2018-06-07
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