Invention Grant
- Patent Title: Beta-lactamase inhibitor and process for preparing the same
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Application No.: US15583238Application Date: 2017-05-01
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Publication No.: US10023573B2Publication Date: 2018-07-17
- Inventor: Takao Abe , Takeshi Furuuchi , Yoshiaki Sakamaki , Seiichi Inamura , Akihiro Morinaka
- Applicant: MEIJI SEIKA PHARMA CO., LTD.
- Applicant Address: JP Chuo-Ku, Tokyo
- Assignee: MEIJI SEIKA PHARMA CO., LTD.
- Current Assignee: MEIJI SEIKA PHARMA CO., LTD.
- Current Assignee Address: JP Chuo-Ku, Tokyo
- Agency: Holtz, Holtz & Volek PC
- Priority: JP2012-122603 20120530
- Main IPC: C07D211/06
- IPC: C07D211/06 ; C07D295/00 ; C07D471/08 ; C07D211/60 ; A61K45/06 ; A61K31/43 ; A61K31/545 ; A61K31/546 ; A61K31/439 ; A61K31/444 ; A61K31/4545 ; A61K31/5377 ; A61K31/437 ; A61K31/407 ; A61K31/4162 ; A61K31/427 ; C07F7/08
Abstract:
A process for preparing a diazabicyclooctane compound represented by the following formula (I): wherein A represents RcO—; B represents NH or NC1-6 alkyl; C represents a benzyl group; Rc represents a C1-6 alkyl group; A is substituted with one substituent Fn1, wherein Fn1 represents an azetidine group; the process including: (a) silylating the compound represented by the following formula (IV-c): wherein in the formula (IV-c), OBn represents benzyloxy, and (b) carrying out an intramolecular urea formation reaction.
Public/Granted literature
- US20170233393A1 BETA-LACTAMASE INHIBITOR AND PROCESS FOR PREPARING THE SAME Public/Granted day:2017-08-17
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