Invention Grant
- Patent Title: Pyrazolo[1,5a]pyrimidine derivatives as IRAK4 modulators
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Application No.: US14975004Application Date: 2015-12-18
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Publication No.: US10023589B2Publication Date: 2018-07-17
- Inventor: Nidhi Arora , Shaoqing Chen , Johannes Cornelius Hermann , Andreas Kuglstatter , Sharada Shenvi Labadie , Clara Jeou Jen Lin , Matthew C. Lucas , Amy Geraldine Moore , Eva Papp , Francisco Xavier Talamas , Jutta Wanner , Yansheng Zhai
- Applicant: Hoffmann-La Roche Inc. , Roche Palo Alto LLC
- Applicant Address: US NJ Nutley US CA Palo Alto
- Assignee: Hoffmann-La Roche Inc.,Roche Palo Alto LLC
- Current Assignee: Hoffmann-La Roche Inc.,Roche Palo Alto LLC
- Current Assignee Address: US NJ Nutley US CA Palo Alto
- Main IPC: C07D495/04
- IPC: C07D495/04 ; C07D487/04
![Pyrazolo[1,5a]pyrimidine derivatives as IRAK4 modulators](/abs-image/US/2018/07/17/US10023589B2/abs.jpg.150x150.jpg)
Abstract:
Compounds of the formula I or II: wherein X, m, Ar, R1 and R2 are as defined herein. The subject compounds are useful for treatment of IRAK-mediated conditions.
Public/Granted literature
- US20160207936A1 PYRAZOLO[1,5a]PYRIMIDINE DERIVATIVES AS IRAK4 MODULATORS Public/Granted day:2016-07-21
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