Invention Grant
- Patent Title: 19-nor neuroactive steroids and methods of use thereof
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Application No.: US15273125Application Date: 2016-09-22
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Publication No.: US10023606B2Publication Date: 2018-07-17
- Inventor: Gabriel Martinez Botella , Boyd L. Harrison , Albert Jean Robichaud , Francesco G. Salituro , Richard Thomas Beresis
- Applicant: SAGE THERAPEUTICS, INC.
- Applicant Address: US MA Cambridge
- Assignee: Sage Therapeutics, Inc.
- Current Assignee: Sage Therapeutics, Inc.
- Current Assignee Address: US MA Cambridge
- Agency: Goodwin Procter LLP
- Priority: WOPCT/CN2013/074319 20130417
- Main IPC: C07J43/00
- IPC: C07J43/00

Abstract:
Provided herein are 3,3-disubstituted 19-nor-steroidal compounds according to Formula (I): and pharmaceutical compositions thereof. Such compounds are contemplated useful for the prevention and treatment of a variety of CNS-related conditions, for example, treatment of sleep disorders, mood disorders, schizophrenia spectrum disorders, disorders of memory and/or cognition, movement disorders, personality disorders, autism spectrum disorders, pain, traumatic brain injury, vascular diseases, substance abuse disorders and/or withdrawal syndromes, tinnitus, status epilepticus.
Public/Granted literature
- US20170233432A1 19-NOR NEUROACTIVE STEROIDS AND METHODS OF USE THEREOF Public/Granted day:2017-08-17
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