Invention Grant
- Patent Title: Methods for reducing chromatin content in protein preparations by treatment with alkyl cations
-
Application No.: US15121686Application Date: 2014-02-27
-
Publication No.: US10023609B2Publication Date: 2018-07-17
- Inventor: Peter Stanley Gagnon
- Applicant: AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH
- Applicant Address: SG Singapore
- Assignee: AGENCY FOR SCIENCE, RESEARCH AND TECHNOLOGY
- Current Assignee: AGENCY FOR SCIENCE, RESEARCH AND TECHNOLOGY
- Current Assignee Address: SG Singapore
- Agency: Pillsbury Winthrop Shaw Pittman LLP
- International Application: PCT/SG2014/000087 WO 20140227
- International Announcement: WO2015/130223 WO 20150903
- Main IPC: C07K1/32
- IPC: C07K1/32 ; B01D15/26 ; C07K1/14 ; C07K1/36 ; C07K16/00 ; B01D15/32 ; B01D15/36 ; B01D15/38
Abstract:
A method of reducing aggregate content in a preparation having a target protein includes contacting the preparation with an alkyl cation to form a mixture, and contacting the mixture with at least one functionalized solid to remove excess alkyl cation.
Public/Granted literature
- US20160362448A1 METHODS FOR REDUCING CHROMATIN CONTENT IN PROTEIN PREPARATIONS BY TREATMENT WITH ALKYL CATIONS Public/Granted day:2016-12-15
Information query
