Invention Grant
- Patent Title: Method of immunization for reducing toxic damaged caused by oligomeric form of the amyloid-beta protein with stable amyloid beta monomers and oligomers
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Application No.: US15599906Application Date: 2017-05-19
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Publication No.: US10023622B2Publication Date: 2018-07-17
- Inventor: Torleif Härd , Anders Sandberg
- Applicant: Torleif Härd , Anders Sandberg
- Applicant Address: SE Gothenburg
- Assignee: ALZINOVA AB
- Current Assignee: ALZINOVA AB
- Current Assignee Address: SE Gothenburg
- Agency: Manelli Selter PLLC
- Agent Jeffrey S. Melcher
- Priority: SE0800842 20080414; SE0802433 20081120
- Main IPC: A61K38/00
- IPC: A61K38/00 ; C07K14/00 ; G01N33/53 ; C07K14/47
Abstract:
The invention provides monomeric and oligomeric amyloid beta peptide isomers that are resistant towards fibrillogenesis and their use as screening reagents or antigens in methods and pharmaceutical preparations for the treatment of Alzheimer's disease and other conditions related to protein misfolding. The invention further provides transgenic animals expressing modified amyloid precursor proteins or amyloid beta peptides.
Public/Granted literature
- US20180030103A1 STABLE AMYLOID BETA MONOMERS AND OLIGOMERS Public/Granted day:2018-02-01
Information query
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