Invention Grant
- Patent Title: Fusion polypeptides comprising an active protein linked to a mucin-domain polypeptide
-
Application No.: US14841809Application Date: 2015-09-01
-
Publication No.: US10023623B2Publication Date: 2018-07-17
- Inventor: Juan Alvarez , Jean Chamoun , Heather C. Losey
- Applicant: Alkermes, Inc.
- Applicant Address: US MA Waltham
- Assignee: Alkermes, Inc.
- Current Assignee: Alkermes, Inc.
- Current Assignee Address: US MA Waltham
- Agency: Elmore Patent Law Group, P.C.
- Agent Darlene Vanstone; Carolyn Elmore
- Main IPC: C07K14/47
- IPC: C07K14/47 ; C07K14/54 ; C07K14/55 ; C07K14/545 ; C07K14/715 ; C07K14/50 ; C07K14/705 ; C07K14/71 ; C07K14/575 ; A61K38/00 ; A61K39/00
Abstract:
The present invention provides fusion proteins comprising a mucin-domain polypeptide covalently linked to an active protein that has improved properties (e.g. pharmacokinetic and/or physicochemical properties) compared to the same active protein not linked to mucin-domain polypeptide, as well as methods for making and using the fusion proteins of the invention.
Public/Granted literature
- US20160052983A1 Fusion Polypeptides Comprising an Active Protein Linked to a Mucin-Domain Polypeptide Public/Granted day:2016-02-25
Information query
