Invention Grant
- Patent Title: Cell line expressing single chain factor VIII polypeptides and uses thereof
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Application No.: US14412823Application Date: 2013-07-05
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Publication No.: US10023628B2Publication Date: 2018-07-17
- Inventor: Susan Low , Jennifer A. Dumont , Alan J. Bitonti
- Applicant: Bioverativ Therapeutics Inc.
- Applicant Address: US MA Waltham
- Assignee: Bioverativ Therapeutics Inc.
- Current Assignee: Bioverativ Therapeutics Inc.
- Current Assignee Address: US MA Waltham
- Agency: Sterne, Kessler, Goldstein & Fox P.L.L.C.
- International Application: PCT/US2013/049460 WO 20130705
- International Announcement: WO2014/008480 WO 20140109
- Main IPC: C07K14/765
- IPC: C07K14/765 ; A61K38/00 ; A61K35/00 ; C07K14/755
Abstract:
The present invention provides cell lines for producing single chain FVIII polypeptides, e.g., chimeric single chain FVIII polypeptides, methods of producing single chain FVIII polypeptides, single chain FVIII polypeptides, and methods of treating Hemophilia A with a single chain Factor VIII polypeptide.
Public/Granted literature
- US20150191526A1 CELL LINE EXPRESSING SINGLE CHAIN FACTOR VIII POLYPEPTIDES AND USES THEREOF Public/Granted day:2015-07-09
Information query
