Invention Grant
- Patent Title: Antigenic GM-CSF peptides and antibodies to GM-CSF
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Application No.: US15212779Application Date: 2016-07-18
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Publication No.: US10023632B2Publication Date: 2018-07-17
- Inventor: Philip M. Sass , Nicholas C. Nicolaides , Luigi Grasso , Wolfgang Ebel , Jian Li , Qimin Chao , Eric Routhier
- Applicant: Morphotek, Inc.
- Applicant Address: US PA Exton
- Assignee: Morphotek, Inc.
- Current Assignee: Morphotek, Inc.
- Current Assignee Address: US PA Exton
- Agency: Baker & Hostetler LLP
- Main IPC: C07K16/24
- IPC: C07K16/24 ; C07K16/22 ; C12N15/09 ; C12N15/13 ; C12N15/63 ; C12P21/08 ; A61K39/395 ; C07K16/00
Abstract:
Hybridoma lines that secrete human monoclonal antibodies with high binding specificity and biological activity, particularly neutralizing activity against granulocyte-macrophage colony stimulating factor, and methods of generating the hybridoma lines are provided. Target antigens and epitopes are also provided. The antibodies may be used in therapeutic methods, for example in the treatment of cancer, infectious disease, or autoimmune disease.
Public/Granted literature
- US20160333089A1 Antigenic GM-CSF Peptides and Antibodies to GM-CSF Public/Granted day:2016-11-17
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