Invention Grant
- Patent Title: Caninized murine antibodies to human PD-1
-
Application No.: US15104838Application Date: 2014-12-19
-
Publication No.: US10023636B2Publication Date: 2018-07-17
- Inventor: Mohamad Morsey , Yuanzheng Zhang , Denise Bartels-Morozov , Jason Erskine , Ian Tarpey , Leonard G. Presta
- Applicant: Intervet Inc.
- Applicant Address: US NJ Madison
- Assignee: Intervet Inc.
- Current Assignee: Intervet Inc.
- Current Assignee Address: US NJ Madison
- International Application: PCT/EP2014/078665 WO 20141219
- International Announcement: WO2015/091914 WO 20150625
- Main IPC: C07K16/28
- IPC: C07K16/28 ; A61K39/00 ; A61K39/395

Abstract:
The present invention provides caninized murine anti-human PD-1 antibodies that have specific sequences and a high binding affinity for canine PD-1. The invention also relates to use of these antibodies in the treatment of dogs.
Public/Granted literature
- US20160319018A1 CANINIZED MURINE ANTIBODIES TO HUMAN PD-1 Public/Granted day:2016-11-03
Information query