Invention Grant
- Patent Title: Processes for the production of chemically-modified heparins
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Application No.: US14898862Application Date: 2014-06-19
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Publication No.: US10023659B2Publication Date: 2018-07-17
- Inventor: Per-Olov Eriksson , Erik Yngve Holmer
- Applicant: DILAFOR AB
- Applicant Address: SE Solna
- Assignee: Dilafor AB
- Current Assignee: Dilafor AB
- Current Assignee Address: SE Solna
- Agency: LeClairRyan PLLC
- Priority: GB1310928.5 20130619
- International Application: PCT/GB2014/051878 WO 20140619
- International Announcement: WO2014/202982 WO 20141224
- Main IPC: A61K31/727
- IPC: A61K31/727 ; C08B37/00
Abstract:
The present invention relates to a process for the production of heparin derivatives having an average molecular weight of from about 4.6 to about 6.9 kDa and an anti-factor Xa activity of less than about 10 IU/mg, comprising the steps of oxidation of unfractionated heparin, depolymerisation and reduction of resulting terminal groups.
Public/Granted literature
- US20160137754A1 NEW PROCESSES FOR THE PRODUCTION OF CHEMICALLY-MODIFIED HEPARINS Public/Granted day:2016-05-19
Information query
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