Invention Grant
- Patent Title: DNA polymerases with improved activity
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Application No.: US15331748Application Date: 2016-10-21
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Publication No.: US10023849B2Publication Date: 2018-07-17
- Inventor: Shawn Suko
- Applicant: Roche Molecular Systems, Inc.
- Applicant Address: US CA Pleasanton
- Assignee: Roche Molecular Systems, Inc.
- Current Assignee: Roche Molecular Systems, Inc.
- Current Assignee Address: US CA Pleasanton
- Agency: Kilpatrick Townsend and Stockton LLP
- Main IPC: C12N9/12
- IPC: C12N9/12 ; C12N1/21 ; C12N15/54 ; C12P19/34

Abstract:
Disclosed are DNA polymerases having increased reverse transcriptase efficiency relative to a corresponding, unmodified polymerase. The polymerases are useful in a variety of disclosed primer extension methods. Also disclosed are related compositions, including recombinant nucleic acids, vectors, and host cells, which are useful, e.g., for production of the DNA polymerases.
Public/Granted literature
- US20170101632A1 DNA POLYMERASES WITH IMPROVED ACTIVITY Public/Granted day:2017-04-13
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