Invention Grant
- Patent Title: Oligomer-conjugate complexes and their use
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Application No.: US14342196Application Date: 2012-08-29
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Publication No.: US10023861B2Publication Date: 2018-07-17
- Inventor: Thazha P. Prakash , Eric E. Swayze , Walter F. Lima , Garth A. Kinberger
- Applicant: Thazha P. Prakash , Eric E. Swayze , Walter F. Lima , Garth A. Kinberger
- Applicant Address: US CA Carlsbad
- Assignee: Ionis Pharmaceuticals, Inc.
- Current Assignee: Ionis Pharmaceuticals, Inc.
- Current Assignee Address: US CA Carlsbad
- Agency: McNeill Baur PLLC
- International Application: PCT/US2012/052884 WO 20120829
- International Announcement: WO2013/033230 WO 20130307
- Main IPC: C07H21/04
- IPC: C07H21/04 ; C12N15/113 ; C12N15/11 ; C07H21/00
Abstract:
Oligonucleotides, chemically-modified oligonucleotides, and oligonucleotide-conjugate complexes for use in research, diagnostics, and/or therapeutics are described herein. In some embodiments, oligonucleotides comprising a stabilized phosphate moiety covalently attached to the 5′-terminal nucleoside are provided.
Public/Granted literature
- US20150018540A1 OLIGOMER-CONJUGATE COMPLEXES AND THEIR USE Public/Granted day:2015-01-15
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