Invention Grant
- Patent Title: RNA-interference by single-stranded RNA molecules
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Application No.: US15258603Application Date: 2016-09-07
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Publication No.: US10023865B2Publication Date: 2018-07-17
- Inventor: Thomas Tuschl , Javier Martinez , Agnieszka Patkaniowska , Henning Urlaub , Reinhard Luehrmann
- Applicant: Max-Planck-Gesellschaft zur Foerderung der Wissenschaften e.V.
- Applicant Address: DE München
- Assignee: Max-Planck-Gesellschaft zur Förderung de Wissenschaften e.V.
- Current Assignee: Max-Planck-Gesellschaft zur Förderung de Wissenschaften e.V.
- Current Assignee Address: DE München
- Agency: Rothwell, Figg, Ernst & Manbeck, P.C.
- Priority: EP02015532 20020710; EP02018906 20020823
- Main IPC: C12N15/11
- IPC: C12N15/11 ; C12N15/113 ; C07K14/47 ; C07K19/00 ; A61K47/54
Abstract:
The present invention relates to sequence and structural features of single-stranded (ss)RNA molecules required to mediate target-specific nucleic acid modifications by RNA-interference (RNAi), such as target mRNA degradation and/or DNA methylation.
Public/Granted literature
- US20170067050A1 RNA-INTERFERENCE BY SINGLE-STRANDED RNA MOLECULES Public/Granted day:2017-03-09
Information query
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