Invention Grant
- Patent Title: Double-stranded polyC:poly(G/I) RNA for immunostimulation and cancer treatment
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Application No.: US15105467Application Date: 2014-12-16
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Publication No.: US10023871B2Publication Date: 2018-07-17
- Inventor: Jacques Rohayem
- Applicant: RiboxX GmbH
- Applicant Address: DE
- Assignee: RiboxX GmbH
- Current Assignee: RiboxX GmbH
- Current Assignee Address: DE
- Agency: St Onge Steward Johnston and Reens LLC
- Priority: EP13197558 20131216
- International Application: PCT/EP2014/078100 WO 20141216
- International Announcement: WO2015/091578 WO 20150625
- Main IPC: C07H21/02
- IPC: C07H21/02 ; A61K48/00 ; C12N15/117 ; A61K39/39 ; A61K45/06 ; C12P19/34 ; A61K39/00
Abstract:
The present invention relates to polyC:poly(G/I) dsRNAs for triggering innate immunity, in particular through toll-like receptor 3 (TLR-3) and, optionally, RIG-I or RIG-I-like receptors (RLRs), as well as compositions and medicaments containing such dsRNAs, methods for their production and their use in medicine, especially immunostimulation and prevention and/or therapy of infections and tumor diseases.
Public/Granted literature
- US20160312224A1 DOUBLE-STRANDED POLYC:POLY(G/I) RNA FOR IMMUNOSTIMULATION AND CANCER TREATMENT Public/Granted day:2016-10-27
Information query
