A method for analog circuit design includes the steps of (A) evaluating an initial population comprising a plurality of initial designs of an analog circuit using a computer to determine to breed a plurality of new designs that satisfy one or more regions of operation or one or more specification criteria, (B) selecting a plurality of subsets of the initial designs based on a plurality of different techniques to establish a plurality of selected designs, (C) recombining some of the selected designs to generate a plurality of recombined designs, and (D) mutating some of the recombined designs to generate the new designs.