Disclosed are devices, systems, apparatus, methods, products, media and other implementations, including a method that includes obtaining hardware-based micro-architectural data, including hardware-based micro-architectural counter data, for a hardware device executing one or more processes, and determining based, at least in part, on the hardware-based micro-architectural data whether at least one of the one or more processes executing on the hardware device corresponds to a malicious process. In some embodiments, determining based on the hardware-based micro-architectural data whether the at least one of the one or more processes corresponds to a malicious process may include applying one or more machine-learning procedures to the hardware-based micro-architectural data to determine whether the at least one of the one or more processes corresponds to the malicious process.