The present disclosure is a method for frame acknowledgment. The method includes upon completion of downlink service data scheduling and resource allocation, allocating feedback resources in the uplink of the present physical frame; or, upon completion of the uplink service data scheduling and resource allocation, allocating feedback resources in the downlink of the next frame for sending a Group ACK response. The method further includes according to the allocated feedback resources, encapsulating the corresponding control signaling used for indicating feedback resource allocation; sending the feedback resource control signaling in a control channel of the physical frame. Also disclosed is a device for frame acknowledgement. In a centralized wireless communication system having an uplink and downlink frame structure, the method and device of the present disclosure realize data packet sending and acknowledgment in the form of MAC frames at the MAC level, and achieve the least acknowledgment delay and high reliability by providing group acknowledgment with minimum complexity, thus facilitating resource scheduling and retransmission scheduling.