Invention Grant
- Patent Title: Muscarinic receptor agonists
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Application No.: US15126935Application Date: 2015-03-19
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Publication No.: US10030035B2Publication Date: 2018-07-24
- Inventor: Miles Stuart Congreve , Giles Albert Brown , Benjamin Gerald Tehan , Mark Pickworth , Julie Elaine Cansfield
- Applicant: Heptares Therapeutics Limited
- Applicant Address: GB Welwyn Garden City
- Assignee: Heptares Therapeutics Limited
- Current Assignee: Heptares Therapeutics Limited
- Current Assignee Address: GB Welwyn Garden City
- Agency: McCarter & English, LLP
- Agent Steven G. Davis; Mei Bai
- Priority: GB1404922.5 20140319
- International Application: PCT/GB2015/050807 WO 20150319
- International Announcement: WO2015/140559 WO 20150924
- Main IPC: C07D519/00
- IPC: C07D519/00 ; A61K31/438 ; A61K31/439

Abstract:
This invention relates to compounds that are agonists of the muscarinic M1 receptor and which are useful in the treatment of muscarinic M1 receptor mediated diseases. Also provided are pharmaceutical compositions containing the compounds and the therapeutic uses of the compounds. Compounds provided are of formula where m, p, q, W, Z, Y, X1, X2, R1, R2 R3 and R4 are as defined herein.
Public/Granted literature
- US20170096437A1 MUSCARINIC RECEPTOR AGONISTS Public/Granted day:2017-04-06
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