A method and apparatus are provided for transmitting data, acknowledgement information and a channel quality indicator (CQI). The method includes multiplexing the CQI and the data mapping a reference signal on a middle symbol in a slot; multiplexing the acknowledgement information and the multiplexed CQI and data by puncturing the CQI or the data; and transmitting the reference signal, and the multiplexed acknowledgement information, CQI and data, wherein the reference signal is transmitted on the middle symbol in the slot, wherein the acknowledgement information is transmitted on two symbols in the slot, which are directly adjacent to the middle symbol, and wherein the CQI and the data are on symbols in the slot except for the middle symbol.