Invention Grant
- Patent Title: Use of neural cells derived from human pluripotent stem cells for the treatment of neurodegenerative diseases
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Application No.: US14181285Application Date: 2014-02-14
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Publication No.: US10039794B2Publication Date: 2018-08-07
- Inventor: Russell A. Kern , Rodolfo Gonzalez , Ibon Garitaonandia
- Applicant: International Stem Cell Corporation
- Applicant Address: US CA Carlsbad
- Assignee: International Stem Cell Corporation
- Current Assignee: International Stem Cell Corporation
- Current Assignee Address: US CA Carlsbad
- Agency: DLA Piper LLP (US)
- Main IPC: A61K39/00
- IPC: A61K39/00 ; A61K35/545 ; C12N5/0797 ; A61K35/30 ; C12N5/074

Abstract:
The present invention is based in part methods for treating neurodegenerative diseases and disorders. Specifically, the present invention disclose methods for treating neurodegenerative disorders suing neural stem cells (NSCs) and/or pluripotent stem cell (PSC) derived neurons or neuron precursor cells. The present invention also discloses methods to induce endogenous dopaminergic neurons to release dopamine and increase the levels of dopamine in a subject.
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