Invention Grant
- Patent Title: Extracts of rosemary or hemerocallis fulva and methods of using same to promote circadian rhythm
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Application No.: US15036479Application Date: 2014-11-13
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Publication No.: US10039798B2Publication Date: 2018-08-07
- Inventor: Bolin Qin , Augustin T. Romero , Tim Romero
- Applicant: IN Ingredients, Inc.
- Applicant Address: US TN Columbia
- Assignee: IN Ingredients, Inc.
- Current Assignee: IN Ingredients, Inc.
- Current Assignee Address: US TN Columbia
- Agency: Dinsmore & Shohl LLP
- International Application: PCT/US2014/065336 WO 20141113
- International Announcement: WO2015/073598 WO 20150521
- Main IPC: A61K36/00
- IPC: A61K36/00 ; A61K36/53 ; A61K36/896 ; A23K20/105 ; A23K20/158 ; A23K20/10 ; A23L33/105 ; A61K31/56 ; A61K36/88 ; A61K31/19

Abstract:
Provided are process of regulating expression of one or more genes or proteins involved in circadian rhythm. A subject such as a cell is administered or contacted to an extract of rosemary, an extract of hemerocallis fulva, or combinations thereof, optionally provided as a component of a dietary supplement. The presence of one or more active agents in the extracts administered at a targeted administration time alters the expression of one or more genes or proteins involved in circadian rhythm, illustratively CLOCK, BMAL1, FBXL3, FBXL21, or SIRT1.
Public/Granted literature
- US20160296581A1 EXTRACTS OF ROSEMARY OR HEMEROCALLIS FULVA AND METHODS OF USING SAME TO PROMOTE CIRCADIAN RHYTHM Public/Granted day:2016-10-13
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