Substitution of game commands with different replacement commands at client devices using substitution reference sets is provided. Substitution reference sets including first and second substitution reference sets may be obtained. The first substitution reference set may indicate substituting of a first command with a second command. The second substitution reference set may indicate substituting of the first command with a third command different from the second command. The first substitution reference set may be provided to a first client device. The second substitution reference set may be provided to a second client device. Responsive to the first substitution reference set being provided, requested game commands at the first client device that match the first command may be substituted with the second command. Responsive to the second substitution reference set being provided, requested game commands at the second client device that match the first command may be substituted with the third command.