Invention Grant
- Patent Title: Method of producing aliphatic aldehyde compound having terminal conjugated diene structure and intermediate therefor
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Application No.: US15473150Application Date: 2017-03-29
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Publication No.: US10040742B2Publication Date: 2018-08-07
- Inventor: Akihiro Baba , Yuki Miyake , Takeshi Kinsho
- Applicant: SHIN-ETSU CHEMICAL CO., LTD.
- Applicant Address: JP Tokyo
- Assignee: SHIN-ETSU CHEMICAL CO., LTD.
- Current Assignee: SHIN-ETSU CHEMICAL CO., LTD.
- Current Assignee Address: JP Tokyo
- Agency: Williams Mullen
- Agent F. Michael Sajovec
- Priority: JP2016-083120 20160418
- Main IPC: C07C43/00
- IPC: C07C43/00 ; C07C41/48 ; C07C45/42 ; C07C43/315 ; C07C41/20 ; C07C41/30 ; C07C43/178 ; C07C45/81 ; C07C45/82 ; C07C47/21

Abstract:
Provided are a method for producing a terminal conjugated dienal compound without an oxidation reaction and a terminal hydroxyacetal compound useful as an intermediate in the method. More specifically, provided are a method for producing an (E)-dienal compound comprising the steps of: a metalation reaction of an alkynal acetal compound (1) to obtain an organic metal compound (2), an addition reaction of (2) to ethylene oxide to obtain a hydroxyalkynal acetal compound (3), a reduction reaction of (3) to obtain an (E)-hydroxyalkenal acetal compound (4), a functional group conversion reaction of (4) to obtain an (E)-alkenal acetal compound (5) having a leaving group X, an elimination reaction of (5) to obtain an (E)-dienal acetal compound (6), and a hydrolysis reaction of (6) to obtain the (E)-dienal compound (7); and others.
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