Invention Grant
- Patent Title: Substituted diaminocarboxamide and diaminocarbonitrile pyrimidines, compositions thereof, and methods of treatment therewith
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Application No.: US15616039Application Date: 2017-06-07
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Publication No.: US10040770B2Publication Date: 2018-08-07
- Inventor: Mercedes Delgado , Jan Elsner , Paul Erdman , Robert Hilgraf , Laurie Ann LeBrun , Meg McCarrick , Mark A. Nagy , Stephen Norris , David A. Paisner , Yoshitaka Satoh , Marianne Sloss , Jayashree Tikhe , Won Hyung Yoon
- Applicant: SIGNAL PHARMACEUTICALS, LLC
- Applicant Address: US CA San Diego
- Assignee: Signal Pharmaceuticals, LLC
- Current Assignee: Signal Pharmaceuticals, LLC
- Current Assignee Address: US CA San Diego
- Agency: Jones Day
- Main IPC: C07D239/48
- IPC: C07D239/48 ; A61K31/505 ; C07D401/12 ; C07D409/12 ; C07D403/12 ; C07D401/04 ; C07D405/12
Abstract:
Provided herein are Diaminopyrimidine Compounds having the following structures: wherein R1, R2, R3, and R4 are as defined herein, compositions comprising an effective amount of a Diaminopyrimidine Compound, and methods for treating or preventing liver fibrotic disorders or a condition treatable or preventable by inhibition of a JNK pathway.
Public/Granted literature
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