Invention Grant
- Patent Title: Synthesis of chirally enriched 2,4-disubstituted tetrahydropyran-4-ol and its derivatives
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Application No.: US15519855Application Date: 2015-10-16
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Publication No.: US10040775B2Publication Date: 2018-08-07
- Inventor: Sujata V. Bhat , Ravindra D. Gaikwad , Kedar R. Vaze
- Applicant: S.H. KELKAR AND COMPANY LTD.
- Applicant Address: IN Mumbai, Maharashtra
- Assignee: S.H. KELKAR AND COMPANY LTD.
- Current Assignee: S.H. KELKAR AND COMPANY LTD.
- Current Assignee Address: IN Mumbai, Maharashtra
- Agency: Rankin, Hill & Clark LLP
- Priority: IN3333/MUM/2014 20141018
- International Application: PCT/IN2015/000390 WO 20151016
- International Announcement: WO2016/059648 WO 20160421
- Main IPC: C07D309/10
- IPC: C07D309/10 ; C11D7/26 ; A61Q15/00 ; C11B9/00 ; A61K8/49
Abstract:
The present invention discloses a process for synthesis of chiral 2,4-disubstituted-tetrahydropyran-4-ol and its derivatives having a general formula (I) comprising of asymmetric reaction of an aliphatic aldehyde and a homoallylic alcohol in the presence of a chiral organocatalyst, and a fragrance and cosmetic composition containing chirally enriched molecules of the said general formula (I) prepared by the aforesaid process.
Public/Granted literature
- US20170247349A1 SYNTHESIS OF CHIRALLY ENRICHED 2,4-DISUBSTITUTED TETRAHYDROPYRAN-4-OL AND ITS DERIVATIVES Public/Granted day:2017-08-31
Information query
