Invention Grant
- Patent Title: Soluble forms of Hendra and Nipah virus F glycoprotein and uses thereof
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Application No.: US12808930Application Date: 2008-12-19
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Publication No.: US10040825B2Publication Date: 2018-08-07
- Inventor: Yee-peng Chan , Christopher Broder
- Applicant: Yee-peng Chan , Christopher Broder
- Applicant Address: US MD Bethesda
- Assignee: The Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc.
- Current Assignee: The Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc.
- Current Assignee Address: US MD Bethesda
- Agency: Morgan, Lewis & Bockius LLP
- International Application: PCT/US2008/087719 WO 20081219
- International Announcement: WO2009/117035 WO 20090924
- Main IPC: C07K14/005
- IPC: C07K14/005 ; A61K39/12 ; C07K16/10 ; A61K39/00

Abstract:
This invention relates to soluble forms of F glycoprotein from Hendra and Nipah virus and to compositions comprising soluble forms of F glycoprotein from Hendra and Nipah virus. This invention further relates to soluble oligomers of F glycoprotein from Hendra and Nipah virus. This invention also relates to nucleic acids encoding soluble forms of F glycoprotein from Hendra and Nipah virus. This invention also relates to diagnostic and therapeutic methods using the soluble forms of F glycoprotein from Hendra and Nipah virus. Further, this invention relates to antibodies, including neutralizing antibodies, and to vaccines for the prevention, diagnosis and treatment of infection by Hendra and Nipah viruses.
Public/Granted literature
- US20110223172A1 Soluble Forms of Hendra and Nipah Virus F Glycoprotein and Uses Thereof Public/Granted day:2011-09-15
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