Invention Grant
- Patent Title: Antibodies against CD106 (VCAM-1)
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Application No.: US14397074Application Date: 2013-04-24
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Publication No.: US10040854B2Publication Date: 2018-08-07
- Inventor: Daniel Clive Anthony , Sandra Jane Campbell , Francis Joseph Carr , Robin Patrick Choudhury , Benjamin Guy Davis , Timothy David Jones , Nicola Ruth Sibson
- Applicant: Isis Innovation Limited
- Applicant Address: GB Oxford
- Assignee: OXFORD UNIVERSITY INNOVATION LIMITED
- Current Assignee: OXFORD UNIVERSITY INNOVATION LIMITED
- Current Assignee Address: GB Oxford
- Agency: Norton Rose Fulbright US LLP
- Priority: GB1207155.1 20120424
- International Application: PCT/GB2013/051037 WO 20130424
- International Announcement: WO2013/160676 WO 20131031
- Main IPC: A61K39/395
- IPC: A61K39/395 ; C07K16/28 ; G01N33/543 ; G01N33/574 ; G01N33/58 ; G01N33/68

Abstract:
The invention provides an antibody or fragment thereof that specifically binds to human endothelial vascular cell adhesion molecule-1 (VCAM-1), wherein the antibody or fragment thereof binds to the extracellular domain of VCAM-1, and wherein the antibody or fragment thereof binds to VCAM-1 when expressed on endothelial cells, wherein the antibody or fragment thereof is a human or humanized antibody, or fragment thereof.
Public/Granted literature
- US20150125878A1 ANTIBODIES AGAINST CD106 (VCAM-1) Public/Granted day:2015-05-07
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