Invention Grant
- Patent Title: Microfluidic three-dimensional osteocyte network reconstructed with microbeads as scaffold
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Application No.: US14490847Application Date: 2014-09-19
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Publication No.: US10041045B2Publication Date: 2018-08-07
- Inventor: Woo Young Lee , Yexin Gu , Qiaoling Sun , Wenting Zhang , Jenny Zilberberg
- Applicant: THE TRUSTEES OF THE STEVENS INSTITUTE OF TECHNOLOGY , HACKENSACK UNIVERSITY MEDICAL CENTER
- Applicant Address: US NJ Hackensack US NJ Hoboken
- Assignee: HACKENSACK UNIVERSITY MEDICAL CENTER,THE TRUSTEES OF THE STEVENS INSTITUTE OF TECHNOLOGY
- Current Assignee: HACKENSACK UNIVERSITY MEDICAL CENTER,THE TRUSTEES OF THE STEVENS INSTITUTE OF TECHNOLOGY
- Current Assignee Address: US NJ Hackensack US NJ Hoboken
- Agency: McCarter & English, LLP
- Agent Beverly W. Lubit
- Main IPC: C12N5/077
- IPC: C12N5/077 ; C12M1/00 ; C12M1/12 ; C12M3/06 ; G01N33/50
Abstract:
A bed of microbeads is used as a foundation for reconstructing a three-dimensional osteocyte network by culturing osteocytes within the bed. The osteocytes are cultured such that they form a network among the microbeads that is capable of simulating the osteocyte network of natural bone. The osteocytes are cultured in a microfluidic device adapted for the purpose.
Public/Granted literature
- US20150086993A1 MICROFLUIDIC THREE-DIMENSIONAL OSTEOCYTE NETWORK RECONSTRUCTED WITH MICROBEADS AS SCAFFOLD Public/Granted day:2015-03-26
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