Various embodiments herein each include at least one of devices, methods, and software for image guided scale calibration. One embodiment, in the form of a method, includes outputting an instruction to place a first weight on a scale being calibrated at a particular location and capturing at least one image of the weight when placed on the scale. The method then processes a captured image of a weight when placed on the scale to determine whether the weight is the first weight and whether the weight is at the particular location. When the weight placed on the scale is not the first weight or the weight is not at the particular location, the method performs a remedial action.