Invention Grant
- Patent Title: Macrophage identification agent, and identification method, sorting method, evaluation method, screening method and kit using the macrophage identifier agent
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Application No.: US14766386Application Date: 2014-05-29
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Publication No.: US10041937B2Publication Date: 2018-08-07
- Inventor: Fumiyo Koide , Tsuyoshi Nomoto , Sachiko Yamauchi , Kohei Watanabe , Taichi Shintou , Takeshi Miyazaki , Yasuhiko Tabata , Eri Sanda
- Applicant: CANON KABUSHIKI KAISHA
- Applicant Address: JP Tokyo
- Assignee: CANON KABUSHIKI KAISHA
- Current Assignee: CANON KABUSHIKI KAISHA
- Current Assignee Address: JP Tokyo
- Agency: Fitzpatrick, Cella, Harper & Scinto
- Priority: JP2013-114578 20130530
- International Application: PCT/JP2014/064900 WO 20140529
- International Announcement: WO2014/192972 WO 20141204
- Main IPC: G01N33/52
- IPC: G01N33/52 ; C07D209/14 ; G01N33/50 ; C12N5/0786 ; C07D401/06 ; C07D403/06 ; C07D403/08 ; C07D413/06 ; C07D413/08 ; C07D417/06 ; C07D417/08 ; C07D417/14 ; C07D209/80 ; C07D277/64 ; C07D413/04 ; C07D498/04 ; C07F5/02
Abstract:
An object of the present invention is to provide an identification method for a macrophage subtype using an organic compound. Another object of the present invention is to provide a macrophage identification agent containing an organic compound in which a spectral characteristic obtained when the organic compound is added is different depending on a macrophage subtype. Still another object of the present invention is to provide an evaluation method for a macrophage subtype using a macrophage identification agent, an analysis method for correlation between a macrophage subtype and a test substance, a screening method for correlation between a macrophage subtype and a test substance, and a kit. An identification method for a macrophage subtype utilizing that a spectral characteristic obtained with an organic compound added is different depending on a macrophage subtype is provided.
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Information query
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