A system and method are provided for adaptively optimized recomposition of a parts list for fabrication of an electronic circuit product. A parts list acquisition portion forms a parts list containing a plurality of constituent parts entries read from one or more predetermined sources. The parts entries are respectively identified in the parts list by different corresponding part identifiers. An optimization unit coupled to the parts list acquisition unit comparatively determines mutual matching between different parts entries based on at least one optimization parameter. The optimization unit intermediately recomposes the parts list by incorporating one or more suggested parts substitutions to adaptively consolidate mutually matched pairs of parts entries. A results exploration unit coupled to the optimization unit actuates a user interface portion to render the intermediately recomposed parts list, and alternatively incorporates or discards the suggested parts substitutions responsive to user input, to generate a fully recomposed parts list.