Energy reduction in a CATV network device, such as an optical node, in a CATV network may be accomplished using a system and method for controlling an amplifier in response to channel loading. The system and method detects a channel loading condition for a CATV RF signal including a plurality of utilized channels across a channel spectrum defining a plurality of potential channels. The channel loading condition may be detected by scanning the CATV RF signal to measure the channel loading or by obtaining channel loading data from a remote PHY device (RPD) located in the optical node. The system and method then obtains an amplifier operating parameter associated with the channel loading condition and applies the amplifier operating parameter to control power consumption of an amplifier in the optical node (e.g., by changing bias current) in response to the channel loading condition.