A novel and simple photonic vector signal generation scheme at radio frequency (RF) bands enabled by a single-drive Mach-Zehnder modulator (MZM)-based optical carrier suppression (OCS) without precoding techniques and optical filter, which can reduce the complexity of transmitter digital signal processing (DSP), is described. The generation and reception of 16/20/22-Gbaud quadrature-phase-shift-keying (QPSK) vector signals at 16/20/22 GHz are experimentally demonstrated, respectively. The measured bit-error ratio for 16G-baud QPSK vector signals after transmitting over 10-km standard single mode fiber (SSMF) can be under 7% hard-decision forward-error-correction (HD-FEC) threshold of 3.8×10−3. Moreover, compared to the conventional precoding scheme, the receiver sensitivity can be enhanced by 4 dB at both back-to-back (BTB) and after 10-km SSMF transmission cases, which demonstrates the feasibility of this technique, and show its potential promising application in radio over fiber (RoF) system.