Methods and systems can suppress invalid defect detection when Out-Of-Frame (OOF) conditions occur within an Optical Transport Network. One method for processing a report of a defect during an OOF condition may include detecting the OOF condition at a downstream node, detecting an indication of the defect caused by the OOF condition, suppressing a report associated with the indication of the defect, determining whether the OOF condition is clear, determining whether the indication of the defect is still present if the OOF condition is clear; and cancelling the report if the indication of the defect is not present. A network node which processes a report of a defect during an OOF condition may include a network interface, and a processor which is coupled to the network interface. The processor may be configured to perform a method for suppressing invalid defect detection during OOF conditions.