Invention Grant
![Selective octahydro-cyclopenta[C] pyrrole negative modulators of NR2B](/docs/US/2018-08-21/US10052306B2/abs.jpg.600x600.jpg)
- Patent Title: Selective octahydro-cyclopenta[C] pyrrole negative modulators of NR2B
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Application No.: US15360824Application Date: 2016-11-23
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Publication No.: US10052306B2Publication Date: 2018-08-21
- Inventor: David R. Anderson , Robert A. Volkmann , Frank S. Menniti
- Applicant: LUC THERAPEUTICS, INC.
- Applicant Address: US MA Cambridge
- Assignee: CADENT THERAPEUTICS, INC.
- Current Assignee: CADENT THERAPEUTICS, INC.
- Current Assignee Address: US MA Cambridge
- Agency: Brinks Gilson & Lione
- Main IPC: A61K31/403
- IPC: A61K31/403 ; C07D209/52 ; C07D403/12 ; C07D401/04 ; C07D401/06 ; C07D401/10 ; C07D401/12 ; C07D403/04 ; C07D403/06 ; C07D403/10 ; C07D403/14 ; C07D413/06 ; C07D205/04 ; C07D401/14 ; C07D487/04 ; A61K31/404 ; A61K31/4192 ; A61K31/423 ; A61K31/4439 ; A61K31/444 ; A61K31/4709 ; A61K31/497 ; A61K31/501 ; A61K31/506
![Selective octahydro-cyclopenta[C] pyrrole negative modulators of NR2B](/abs-image/US/2018/08/21/US10052306B2/abs.jpg.150x150.jpg)
Abstract:
Compounds that selectively negatively modulate NMDA receptors containing an NR1/NR2B subunit, pharmaceutical compositions comprising the compounds, and methods of treating a disease using the compounds are disclosed.
Public/Granted literature
- US20170071906A1 SELECTIVE OCTAHYDRO-CYCLOPENTA[C] PYRROLE NEGATIVE MODULATORS OF NR2B Public/Granted day:2017-03-16
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