Invention Grant
- Patent Title: Cyclopropanamine compound and use thereof
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Application No.: US15302405Application Date: 2015-04-09
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Publication No.: US10053456B2Publication Date: 2018-08-21
- Inventor: Shigemitsu Matsumoto , Yasushi Hattori , Masashi Toyofuku , Shinji Morimoto , Masaki Daini , Takuto Kojima , Tomohiro Kaku , Mitsuhiro Ito
- Applicant: Takeda Pharmaceutical Company Limited
- Applicant Address: JP Osaka
- Assignee: Takeda Pharmaceutical Company Limited
- Current Assignee: Takeda Pharmaceutical Company Limited
- Current Assignee Address: JP Osaka
- Agency: Hamre, Schumann, Mueller & Larson, P.C.
- Priority: JP2014-082057 20140411
- International Application: PCT/JP2015/061651 WO 20150409
- International Announcement: WO2015/156417 WO 20151015
- Main IPC: C07D417/14
- IPC: C07D417/14 ; C07D307/81 ; C07D231/12 ; C07D277/56 ; C07D409/14 ; C07D413/12 ; C07D413/14 ; C07D285/135 ; C07D285/08 ; C07D333/40 ; C07D231/14 ; C07D333/38 ; C07D407/12 ; C07D307/79 ; C07D409/12 ; C07D417/12 ; C07D213/82

Abstract:
The present invention provides a compound having a lysine-specific demethylase-1 inhibitory action, and useful as a medicament such as a prophylactic or therapeutic agent for schizophrenia, developmental disorders, particularly diseases having intellectual disability (e.g., autistic spectrum disorders, Rett syndrome, Down's syndrome, Kabuki syndrome, fragile X syndrome, Kleefstra syndrome, neurofibromatosis type 1, Noonan syndrome, tuberous sclerosis), neurodegenerative diseases (e.g., Alzheimer's disease, Parkinson's disease, spinocerebellar degeneration (e.g., dentatorubural pallidoluysian atrophy) and Huntington's disease), epilepsy (e.g., Dravet syndrome) or drug dependence, and the like. A compound represented by the formula wherein each symbol is as defined in the present specification, or a salt thereof.
Public/Granted literature
- US20170029417A1 CYCLOPROPANAMINE COMPOUND AND USE THEREOF Public/Granted day:2017-02-02
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