Invention Grant
- Patent Title: Tetracyclic 4-oxo-pyridine-3-carboxylic acid derivatives for the treatment and prophylaxis of hepatitis B virus infection
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Application No.: US15867010Application Date: 2018-01-10
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Publication No.: US10053461B2Publication Date: 2018-08-21
- Inventor: Xingchun Han , Min Jiang , Yongguang Wang , Song Yang
- Applicant: Hoffmann-La Roche Inc.
- Applicant Address: US NJ Little Falls
- Assignee: Hoffmann-La Roche Inc.
- Current Assignee: Hoffmann-La Roche Inc.
- Current Assignee Address: US NJ Little Falls
- Agent Brian L. Buckwalter
- Priority: WOPCT/CN2015/085191 20150727
- Main IPC: C07D471/06
- IPC: C07D471/06 ; A61K31/4745 ; C07D471/14 ; C07D455/06 ; C07D491/147 ; C07D495/14 ; A61P31/20

Abstract:
The invention provides novel compounds having the general formula: wherein R1 to R6, V, W, X and Y are as described herein, compositions including the compounds and methods of using the compounds.
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