Invention Grant
- Patent Title: Phosphohistidine and phosphotyrosine analogues
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Application No.: US14914994Application Date: 2014-09-02
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Publication No.: US10053476B2Publication Date: 2018-08-21
- Inventor: Richard Jackson , Richmond Muimo , Matthew Lilley
- Applicant: UNIVERSITY OF SHEFFIELD
- Applicant Address: GB Sheffield
- Assignee: UNIVERSITY OF SHEFFIELD
- Current Assignee: UNIVERSITY OF SHEFFIELD
- Current Assignee Address: GB Sheffield
- Agency: McCarter & English, LLP
- Agent Steven G. Davis; Joshua J. Galgano
- Priority: GB1315751.6 20130904
- International Application: PCT/GB2014/052646 WO 20140902
- International Announcement: WO2015/033120 WO 20150312
- Main IPC: A61K39/385
- IPC: A61K39/385 ; C07F9/6503 ; C07F9/6539 ; C07K16/44 ; G01N33/53 ; C07F9/58 ; C07F9/6553 ; C07K14/00
Abstract:
The invention relates to phosphohistidine analogs. The invention also relates to antibodies that specifically bind to the analogs and methods of generating said antibodies. In one embodiment of the invention there is provided a phosphohistidine analog of Formula V: (V) wherein W is selected from H, CO2H or CONH2; and X is selected from CH or N.
Public/Granted literature
- US20160207948A1 PHOSPHOHISTIDINE AND PHOSPHOTYROSINE ANALOGUES Public/Granted day:2016-07-21
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