Invention Grant
- Patent Title: Method for producing peptide hydrazide, peptide amide, and peptide thioester
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Application No.: US15146589Application Date: 2016-05-04
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Publication No.: US10053491B2Publication Date: 2018-08-21
- Inventor: Akira Otaka , Akira Shigenaga , Masakazu Sugiyama , Hidemi Fujii
- Applicant: AJINOMOTO CO., INC.
- Applicant Address: JP Tokyo
- Assignee: AJINOMOTO CO., INC.
- Current Assignee: AJINOMOTO CO., INC.
- Current Assignee Address: JP Tokyo
- Agency: Oblon, McClelland, Maier & Neustadt, L.L.P.
- Priority: JP2013-229717 20131105
- Main IPC: C07K1/107
- IPC: C07K1/107 ; C07K7/06 ; C07K1/13 ; C07K1/00 ; C07D249/00
Abstract:
An object of the present invention is to provide a method for producing a peptide thioester compound, a peptide hydrazide compound, and a peptide amide compound. The present invention provides a method for producing a peptide hydrazide compound or a peptide amide compound by using a compound represented by Formula (2): wherein R1, R2, R3, and X are as defined in the specification, and using a hydrazine compound or an ammonia compound as a reaction reagent. The present invention also provides a method for producing a peptide thioester compound from the peptide hydrazide compound.
Public/Granted literature
- US20160264626A1 METHOD FOR PRODUCING PEPTIDE HYDRAZIDE, PEPTIDE AMIDE, AND PEPTIDE THIOESTER Public/Granted day:2016-09-15
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