Invention Grant
- Patent Title: Heterologous production of patchoulol, β-santalene, and sclareol in moss cells
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Application No.: US14901320Application Date: 2014-05-07
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Publication No.: US10053703B2Publication Date: 2018-08-21
- Inventor: Henrik Simonsen , Dong-Fang Chen , Xin Zhan , Xiwu Pan , Brian Christopher King
- Applicant: UNIVERSITY OF COPENHAGEN , FIRMENICH SA
- Applicant Address: DK Copenhagen CH Geneva
- Assignee: UNIVERSITY OF COPENHAGEN,FIRMENICH SA
- Current Assignee: UNIVERSITY OF COPENHAGEN,FIRMENICH SA
- Current Assignee Address: DK Copenhagen CH Geneva
- Priority: DK201370367 20130628
- International Application: PCT/DK2014/050130 WO 20140507
- International Announcement: WO2014/206412 WO 20141231
- Main IPC: C12N5/14
- IPC: C12N5/14 ; C12P7/02 ; C12N5/00 ; C12N15/82 ; C12P15/00 ; C12P5/00
Abstract:
The present invention relates to methods for preparing patchoulol, β-santalene, and sclareol in transgenic moss cells that include heterologous nucleic acid molecules encoding a polypeptide or synthase capable of using FPP or GGPP as a substrate. Methods for producing the transgenic moss cell, as well as the transgenic moss cell itself are also disclosed.
Public/Granted literature
- US20160222401A1 HETEROLOGOUS PRODUCTION OF PATCHOULOL, BETA-SANTALENE, AND SCLAREOL IN MOSS CELLS Public/Granted day:2016-08-04
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