Systems and methods for simulating optical sensor response data for fluids in a wellbore are disclosed herein. A system comprises a downhole tool, an optical sensor coupled to the downhole tool, and a sensor information mapping module. The sensor information mapping module is operable to receive sensor response information associated with the optical sensor and a first fluid, receive sensor spectra information associated with the optical sensor, and receive fluid spectroscopy information associated with the first fluid. The sensor information mapping module is also operable to determine a transformation matrix using the sensor response information, the sensor spectra information, and the fluid spectroscopy information, and determine, using the transformation matrix, simulated sensor response information associated with the optical sensor and a second fluid.