An unmanned autonomous vehicle (aerial or ground) assessment and reporting system may conduct micro scans of interior portions of a structure, such as walls, windows, doorways, stairs, and the like. Scan data from one or more sensor types may be compared with stored profile data from a library of profiles using computer vision or other matching techniques to identify characteristics, defects, damage, construction materials, etc. An adaptive response system may modify the types of sensors used for scanning and/or the scanning pattern itself based on matched profile data. Modifications to the scanning process are implemented in real-time based on identified characteristics of the interior portions of the structure.