A multi-resolution foveated laparoscope (MRFL) addresses a number of the clinical limitations described in the background section. The MRFL technology can (1) simultaneously obtain both wide-angle- and high-magnification images of a surgical area in real-time in a single, fully integrated scope, (2) yield ultra-high spatial resolution which is over 3 times better than a standard laparoscope (SL) at a close-up working distance, (3) automatically scan and engage the high-magnification imaging probe to any sub-region of the surgical field through region-of-interest (ROI) tracking capabilities, (4) vary the optical magnification of the high-resolution imaging probe without the need of physically advancing or withdrawing the scope, (5) maintain a low-length profile, optimized for operating at a long working distance (WD), providing both superb spatial awareness and high-magnification views simultaneously. It allows the scope to be secured to the camera port with reduced conflicts with other surgical instruments in single port access procedures (SPA).