Invention Grant
- Patent Title: Method for treating depression and/or depression status with substituted quinoxaline compounds
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Application No.: US15495862Application Date: 2017-04-24
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Publication No.: US10064879B2Publication Date: 2018-09-04
- Inventor: Nobuaki Ito , Hirofumi Sasaki , Kuninori Tai , Tomoichi Shinohara
- Applicant: OTSUKA PHARMACEUTICAL CO., LTD.
- Applicant Address: JP Tokyo
- Assignee: OTSUKA PHARMACEUTICAL CO., LTD.
- Current Assignee: OTSUKA PHARMACEUTICAL CO., LTD.
- Current Assignee Address: JP Tokyo
- Agency: Finnegan, Henderson, Farabow, Garrett & Dunner, LLP
- Priority: JP2010-204747 20100913
- Main IPC: C07D241/36
- IPC: C07D241/36 ; A61K31/695 ; A61K31/498 ; A61K31/551 ; A61K31/5377 ; A61K31/538 ; A61K31/501

Abstract:
A heterocyclic compound represented by the general formula (1) or a salt thereof: wherein m, l, and n respectively represent an integer of 1 or 2; X represents —O— or —CH2—; R1 represents hydrogen, a lower alkyl group, a hydroxy-lower alkyl group, a protecting group, or a tri-lower alkylsilyloxy-lower alkyl group; R2 and R3, which are the same or different, each independently represent hydrogen or a lower alkyl group; or R2 and R3 are bonded to form a cyclo-C3-C8 alkyl group; and R4 represents an aromatic group or a heterocyclic group, wherein the aromatic or heterocyclic group may have one or more arbitrary substituent(s).
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