Invention Grant
- Patent Title: Immunoconjugates with an intracellularly-cleavable linkage
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Application No.: US15587526Application Date: 2017-05-05
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Publication No.: US10064957B2Publication Date: 2018-09-04
- Inventor: Serengulam V. Govindan , Sung-Ju Moon , David M. Goldenberg
- Applicant: Immunomedics, Inc.
- Applicant Address: US NJ Morris Plains
- Assignee: Immunomedics, Inc.
- Current Assignee: Immunomedics, Inc.
- Current Assignee Address: US NJ Morris Plains
- Agent Richard A. Nakashima
- Main IPC: A61K39/395
- IPC: A61K39/395 ; A61K47/48 ; A61K47/68 ; C07K16/10 ; C07K16/28 ; C07K16/30 ; C07D491/22 ; A61K31/4745 ; C07K16/18 ; A61K45/06 ; A61N5/10 ; A61K39/00
Abstract:
The present invention relates to therapeutic conjugates with improved ability to target various diseased cells containing a targeting moiety (such as an antibody or antibody fragment), a linker and a therapeutic moiety, and further relates to processes for making and using the conjugates.
Public/Granted literature
- US20170239368A1 Immunoconjugates with an Intracellularly-Cleavable Linkage Public/Granted day:2017-08-24
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