Invention Grant
- Patent Title: α-ketoacylic isoniazid compounds, process for producing said compounds, use of the compounds in the treatment of tuberculosis
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Application No.: US15543937Application Date: 2016-01-14
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Publication No.: US10065927B2Publication Date: 2018-09-04
- Inventor: Núbia Boechat , Frederico Silva Castelo Branco
- Applicant: FUNDAÇÃO OSWALDO CRUZ (FIOCRUZ)
- Applicant Address: BR Rio de Janeiro
- Assignee: FUNDACÃO OSWALDO CRUZ (FIOCRUZ)
- Current Assignee: FUNDACÃO OSWALDO CRUZ (FIOCRUZ)
- Current Assignee Address: BR Rio de Janeiro
- Agency: Kilpatrick Townsend & Stockton LLP
- Priority: BR102015000922 20150115
- International Application: PCT/BR2016/000004 WO 20160114
- International Announcement: WO2016/112447 WO 20160721
- Main IPC: A61K31/44
- IPC: A61K31/44 ; C07D213/86
Abstract:
The instant invention relates to compounds of formula I wherein: R is selected from H, Me or Cl, and R′ is selected from: H, NH2, NHCOCH3 NHCOCF3 or NHCOCH2Cl. The invention further provides a process for obtaining the compounds of formula I and their use.
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