Invention Grant
- Patent Title: Aminotriazine derivative and pharmaceutical composition comprising the same
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Application No.: US15637967Application Date: 2017-06-29
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Publication No.: US10065941B2Publication Date: 2018-09-04
- Inventor: Hiroyuki Kai
- Applicant: Shionogi & Co., Ltd.
- Applicant Address: JP Osaka
- Assignee: SHIONOGI & CO., LTD.
- Current Assignee: SHIONOGI & CO., LTD.
- Current Assignee Address: JP Osaka
- Agency: Finnegan, Henderson, Farabow, Garrett & Dunner, LLP
- Priority: JP2013-125134 20130614
- Main IPC: C07D401/12
- IPC: C07D401/12 ; C07D405/14 ; C07D409/14 ; A61K31/53 ; A61P25/04

Abstract:
The present invention provides novel compounds having a P2X3 and/or P2X2/3 receptor antagonistic activity.A compound of Formula (I): wherein Ra and Rb, and Rd and Re are taken together to form oxo or the like; R4a and R4b are hydrogen or the like; n is 1 or the like; R2 is aryl or the like; s and s′ is 0 or the like; R9 and R9′ are halogen or the like; R20a and R20b are hydrogen, alkyl or the like; u is 1 to 4; R13 is hydrogen or the like, or its pharmaceutically acceptable salt.
Public/Granted literature
- US20170362199A1 AMINOTRIAZINE DERIVATIVE AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME Public/Granted day:2017-12-21
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